Ayatollah Khamenei has firmly rejected the prospect of direct US-Iran talks, but his remarks should be read in the context of Iran's fractured domestic politics. Iran's talks with the P5+1 must progress first.
The deployment of Patriot missiles to Turkey in response to the ongoing Syrian civil war makes sense strategically and underscores NATO's relevance. However, they also hamper Turkey's role to seek accommodation with her neighbours.
The Syrian regime has accused Israel of, as yet, unconfirmed attacks against Syrian military installations. Nevertheless, it is unlikely that such a move will trigger a retaliation or threaten a regional war.
The end of ambiguity about Pyongyang's nuclear capacity raises fundamental questions affecting China, the United States, and the future of international non-proliferation strategy. Indirectly, these consequences could actually work to the advantage of the West in its attempts to prevent Iran 'going nuclear'.